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Artificial intelligence (AI) is fundamentally reshaping biotechnology and healthcare, unlocking the secrets hidden within complex biological data.

Machine learning in genomics and proteomics is transforming how diseases are detected, monitored and treated. Central to this revolution are innovative platforms tackling some of medicine’s toughest challenges, integrating AI with molecular biology to accelerate drug development, improve diagnostics and personalize patient care.

This wave of AI-driven biotechnology not only promises to improve lives by addressing unmet medical needs but also offers investors a rare opportunity to support scalable, data-rich solutions, setting the stage for potential disruptive growth in healthcare.

AI unlocking biological complexity: From data to decision

The challenge of interpreting vast amounts of biological data, which has long slowed progress in disease detection and drug discovery, is precisely where AI offers a valuable solution.

For example, liquid biopsy, which analyzes DNA fragments circulating in the blood, exemplifies AI’s power to break new ground. Unlike invasive tissue biopsies, liquid biopsy offers a minimally invasive window into the body’s molecular makeup.

However, signals in blood can be extremely subtle, especially for chronic diseases like liver conditions, which have eluded detection with older methods. Transformer-based AI models adapted to biological data can analyze millions of molecular interactions simultaneously, uncovering faint patterns and signatures that traditional methods miss, enabling early detection and personalized diagnostics that can dramatically improve outcomes.

Hepta, a liquid biopsy company developed by experts from Illumina (NASDAQ:ILMN) and GRAIL, Inc. (NASDAQ:GRAL), has created an AI platform that analyzes epigenetic patterns in circulating cell-free DNA.

The company recently came out of stealth mode with US$6.7 million in seed funding led by Felicis Ventures and Illumina Ventures, among others. Its technology is designed to replace invasive biopsies with simple blood draws, showing strong early clinical results for detecting liver disease.

CEO Hamed Amini described how Hepta’s platform is uniquely designed from the ground up to deliver a specialized approach that sets it apart from earlier AI tools used in cancer research, opening the door to new possibilities for broad applications.

“I think in the not-distant future, we’re going to be at a place where generating ample genomic data is truly not going to be a cost barrier anymore,” he said. “Once you get there, I envision a super comprehensive central assay that captures all this epigenetic signal from a blood sample (to determine patient eligibility for certain treatments). You can expand this to oncology and other chronic diseases down the line, hopefully.’

AI accelerates drug discovery and personalizes cancer care

AI is also drastically transforming cancer care by accelerating drug discovery and development, with the potential to revolutionize medicine, according to an editorial in the Lancet Oncology. Author Abhishek Mehta observes that many academic cancer centers are collaborating with private companies to use AI for optimizing drug development, trials and analytics.

For example, the cancer drug BBO-10203 was developed by researchers at Lawrence Livermore National Laboratory and Frederick National Laboratory for Cancer Research in collaboration with private biotech company BridgeBio Oncology Therapeutics. Developers used advanced computing and AI to go from conception to human trials in just six years. This is a stark improvement to the 10 to 15-year timeline of the traditional drug development process.

Other key innovators include Rakovina Therapeutics (TSXV:RKV), a Canadian biotech company, which is using its AI platforms, Deep-Docking and Enki, to help discover drugs that target the DNA damage repair process in cancer cells.

One of its main programs is a therapy that blocks a key protein that cancer cells need to survive. Rakovina has found promising candidates and is working with top cancer research centers to move these treatments toward human trials.

Recently, it has partnered with a biotech company specializing in advanced lipid nanoparticle technology designed with AI assistance to develop AI-discovered cancer therapies. The company has also expanded access for US investors through new trading eligibility.

Beyond optimizing drug candidates and delivery mechanisms, AI is also being deployed to develop targeted therapeutic strategies.

“The next improvement in human life and survival comes from the next platform shift, and we really believe that metabolism is that, and this trial would allow us to really open that door for people in their minds,” Parikh explained, adding that the complexity of metabolic function necessitates the need for machine learning. “There are no approaches around metabolism and cancer that can thrive and survive and be reproducible without leveraging machine learning.”

Personalized, data-driven healthcare’s expanding frontier

Looking ahead, AI is reshaping drug development pipelines, with techniques like DeepDR and SNF-CVAE expected to enhance drug discovery and repurposing, speeding up clinical timelines.

For investors, the economic implications of such efficiency gains are profound: faster approvals and lower development costs can significantly increase returns while reducing risk.

Not only will AI tools help pharmaceutical companies select promising candidates faster and design smarter trials, but industry insiders maintain that they can eventually help physicians personalize therapies to patient-specific profiles.

In Faeth’s case, its AI-driven MetabOS platform reduces the data related to cancer metabolism to a smaller, more tractable set of potential targets. Then, CRISPR gene-editing technology allows further experimental validation and refinement to identify the most promising therapeutic candidates with high precision.

“There’s a cohort of patients .. .that are really benefiting,” Parikh said of the DICE trial. “And so we’re going to figure out who those patients are, and then make sure physicians are getting those patients on it early so they can derive the maximum benefit.”

However, widespread adoption faces hurdles, including regulatory pathways and data quality standards; still, growing investor interest and strategic partnerships indicate strong momentum in overcoming these barriers. As Parikh said, “If the data … (are good), more capital will come.”

For example, Danish medical AI company Corti is increasingly finding traction by offering healthcare institutions “AI infrastructure” designed specifically for medical use cases

Governments are also investing heavily in AI for disease research, exemplified by the US$500 billion US Stargate Project, which includes funding allocated to AI-driven biomedical research and infrastructure development; and the UK’s £19 million PharosAI initiative supporting AI-powered cancer research and clinical innovation.

The bottom line

AI-driven platforms are on the frontline of healthcare innovation.

For investors with an eye toward the future, this is an opportunity to support transformative science while participating in a market with tremendous growth potential. This is not just about technology; it’s about changing how medicine is practiced and ultimately, how lives are improved and saved.

Securities Disclosure: I, Meagen Seatter, hold no direct investment interest in any company mentioned in this article.

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Bert Dohmen, founder and CEO of Dohmen Capital Research, discusses precious metals.

He believes gold’s fundamentals support ‘much higher prices’ for a number of years, and sees silver doing even better as the US faces down the specter of potential deflation.

Securities Disclosure: I, Charlotte McLeod, hold no direct investment interest in any company mentioned in this article.

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For years, rare earths have been discussed mostly in times of crisis — a supply scare here, a geopolitical flare there. This year, the strategic minerals are again taking center stage as China reasserts control over the sector.

The latest round of rare earths policy shifts has put new attention on how producers outside China are positioning themselves. For MP Materials (NYSE:MP), 2025 has been less about responding to market turbulence and more about testing what a viable, strategically resilient rare earths supply chain could look like beyond China’s dominance.

“We’ve been talking about these issues for many, many years,” CFO Ryan Corbett said during a fireside chat at the Benchmark Week conference in Marina del Rey, California.

“But the export controls in April put everything in stark relief.” The result, he told the audience, has been a level of public and government attention he has “never seen before.”

And the attention is coming at a pivotal moment for the US-based company.

This year marked five years since MP went public, an anniversary the team celebrated by ringing the bell at the New York Stock Exchange, as well as the culmination of several major announcements aimed at strengthening rare earths production, processing and magnet making outside of China.

The long road from mine to magnet

Corbett is the first to admit that the broader conversation around rare earths often oversimplifies the challenge. Headlines usually focus on mining or magnets, but the real bottlenecks, he stressed, live in the middle.

“You don’t magically take NdPr oxide and turn it into a magnet in a magnet factory,” he said. The process includes converting oxide to metal, metal to alloy flake, flake to powder, then pressing, sintering, slicing and grinding. Each step requires specific infrastructure, technical expertise and — perhaps most critically — experience.

Corbett sees this gap clearly in the wake of announcements from companies claiming to have plans for large-scale magnet facilities. “We see all these announcements — ‘We’re going to do a 10,000 ton magnet plant.’ They’ve never made metal before,” he said. “Good luck. It takes time. It takes investment. It takes R&D.”

When MP listed publicly five years ago, it was still producing only rare earths concentrate. The company told investors it would revisit magnet-making discussions around 2025.

Geopolitical urgency pushed MP to accelerate that timeline, leading to the company’s fully integrated US facility in Fort Worth, where metal, alloy and finished magnets are now all made domestically.

“It is critical that we master all of them at scale,” Corbett said. Without that know-how, any new facility will be vulnerable to single-point failures, the same dynamic that has left the industry heavily reliant on China.

Where the real rare earths bottleneck lies

When asked what truly slows down western rare earths supply chain development, Corbett didn’t point to mining. Instead, he pointed to refining, a stage China has dominated for decades.

“China doesn’t have 99 percent of the upstream reserves,” he noted. “They have the refining capacity and capability.”

That distinction is shaping MP’s next major step: a new world-scale refining facility in Saudi Arabia, built in partnership with Maaden and backed by the US Department of Defense (DoD).

The project is designed to process feedstocks from around the world, including materials that are too small, too short-lived or too geographically constrained to justify their own refineries.

Crucially, the new plant is being built with capital from the US government, not MP. “We didn’t want to be putting more capital at risk overseas while we’re fulfilling promises in the US,” Corbett said.

He added that the government wanted the facility built, and MP brought the technical and operational capability; the equity investment from the DoD bridged the gap.

The structure is unusual. According to Corbett, this is the first time since World War II that the DoD has taken an equity stake in a private enterprise. But he argued that the situation demands it.

“From a supply chain and national security perspective, we are that far behind.”

A price floor that reshapes incentives

The DoD’s involvement isn’t limited to the Saudi facility.

This past summer, the department also struck a landmark agreement with MP, establishing a price floor for NdPr oxide, the high-value rare earths ingredient inside permanent magnets.

The deal is “absolutely transformational,” Corbett said.

Rare earths prices have historically been highly vulnerable to sudden moves from China, a fact that has long posed an existential risk to western refiners. “What good is it to invest billions of dollars if the second you turn your refinery on, prices go from US$170 to US$45?” questioned Corbett.

The agreement is structured to avoid distorting the downstream market. MP still sells oxide at market prices; the government covers the difference only when prices fall below the negotiated threshold.

“It doesn’t impact the pricing of our magnets at all,” Corbett explained. “That was really important to us.”

If prices soar — something Corbett says he would welcome — MP would pay the government.

“I hope five years from now I’m being accosted by investors for taking this deal, because prices are so high we’re cutting checks back to the government,” he said.

Apple, recycling and the next phase

Also over the summer, MP announced another milestone — a major partnership with Apple (NASDAQ:AAPL) to source 100 percent recycled rare earth materials for the tech giant’s devices.

Recycling is often framed as a threat to miners. Corbett argues the opposite.

“It’s still a game of scale and expertise in refining,” he said. “It’s just a different feedstock.”

In many ways, recycled magnets are easier to process than raw ore. The challenge is achieving sufficient volume and consistency, something MP believes Mountain Pass is uniquely positioned to enable.

“Integration matters,” Corbett said. By blending recycled materials with the mine’s large, steady feedstock, MP can smooth out the variability inherent in end-of-life magnets.

A new playbook for national resources?

Taken together, MP’s 2025 announcements point toward a broader shift in how western governments approach critical minerals supply chains moving forward. Heavy government involvement through frameworks like equity stakes, price floors and international partnerships may represent a new template.

“This administration is approaching it with the mentality that it’s going to take real dollars to make this happen,” Corbett said. And if its investments pay off, he argued, they could help rebuild an industrial base the US hasn’t had in decades as MP positions itself to offer the full value chain, from mining and refining to producing finished magnets.

“Once the flywheel gets going,” Corbett said, “You’re onto something.”

Securities Disclosure: I, Georgia Williams, hold no direct investment interest in any company mentioned in this article.

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Homerun Resources Inc. (TSXV: HMR,OTC:HMRFF) (OTCQB: HMRFF) (‘Homerun’ or the ‘Company’) is pleased to announce that it has received TSXV conditional approval for its previously announced financing, originally announced on June 16, 2025, with an arm’s length institutional investor, Sorbie Bornholm LP (the ‘Investor’) in connection with a proposed financing for CDN$6,000,000.00 (the ‘Offering’) at a price of $1.00 per unit (‘Unit’).

The Offering will consist of the issuance of 6,000,000 Units. Each Unit shall be comprised of one (1) common share (‘Shares‘) of the Company and one (1) common share purchase warrant (‘Warrants‘). The proceeds from the Offering will be used to advance the Company’s vertically integrated silica to solar and energy storage business, supporting business development and scaling of revenues and for general working capital purposes.

Brian Leeners, CEO of Homerun stated, ‘We are thrilled to welcome this particular Institutional Investor as they have chosen Homerun to be their inaugural investment with a company trading on the TSX Venture Exchange. Their innovative investment model provides capital over 24 months keeping our team focused on the execution of our plans and deliverables. We have confidence that this financing based on its unique model, will provide capital premiums to the original financing amount over that 24-month period as we continue to de-risk our business and transition into a high-growth, revenue-generating Company with exceptional long-term potential.’

Sorbie Bornholm Managing Director Whitney Kofford commented, ‘Sorbie is proud to announce this new investment in Homerun Resources and to provide Homerun with flexible, growth-linked capital over the next two years through our unique Sharing Agreement. The global energy transition requires bold thinking and the ability to execute on transformative ideas. Homerun’s integrated strategy for high-purity silica and advanced energy solutions is a prime example of just that – innovation meeting opportunity. We applaud Homerun’s consistent track record of hard work and determination, and we look forward to supporting the Company over the longer-term throughout their growth trajectory.’

Pursuant to the terms and conditions of a Sharing Agreement between the parties, the following structure and sequence will take effect under the Offering:

  • The Investor will deposit CDN$6,000,000 into a third-party escrow account.
  • The Company will issue the 6,000,000 Shares into escrow and the Warrants will be issued to Sorbie on each monthly settlement date.
  • Over a 24-month period, the cash and Shares will be released monthly based on the Company’s market price at each release date.
  • The Investor will immediately receive upon closing 1,500,000 Warrants exercisable at CDN$1.18 for three (3) years.
  • The Investor will also receive up to 4,500,000 additional Warrants, issued monthly over 24 months, priced at a 20% premium to the 5-day VWAP at the time of each issuance and exercisable for three (3) years from issuance.
  • The Company will pay the Investor a corporate finance fee of 360,000 Shares and a due-diligence deposit of 100,000 Shares, both subject to the same escrow and release schedule.
  • The Warrants will also include an equity blocker provision that prohibits the Investor from exercising any portion of the Warrants if such exercise would result in the holder owning more than 9.99% of the Company’s outstanding Shares.

The Company intends to rely on the listed issuer financing exemption under Part 5A of National Instrument 45-106 – Prospectus Exemptions, as amended by Coordinated Blanket Order 45-935 – Exemptions from Certain Conditions of the Listed Issuer Financing Exemption, for the Offering, and the Shares and Warrants will not be subject to restrictions on resale. There will be an offering document related to the Offering that will be available under the Company’s profile at www.sedarplus.ca and at www.homerunresources.com. Prospective investors should read this offering document before making an investment decision. Closing of the Offering is subject to several conditions, including receipt of all necessary corporate and regulatory approvals, including the TSXV.

The Offering is expected to close on or about November 30, 2025, or such other date as the Company may determine, and is subject to certain conditions including, but not limited to, the receipt of all necessary regulatory and other approvals, including the final approval of the TSX Venture Exchange. There are no finder’s fees payable to any parties under the Offering.

About Homerun (www.homerunresources.com)

Homerun is building the silica-powered backbone of the energy transition across four focused verticals: Silica, Solar, Energy Storage, and Energy Solutions. Anchored by a unique high-purity low-iron silica resource in Bahia, Brazil, Homerun transforms raw silica into essential products and technologies that accelerate clean power adoption and deliver durable shareholder value.

  • ⁠Silica: Secure supply and processing of high-purity low-iron silica for mission-critical applications, enabling premium solar glass and advanced energy materials.
  • Solar: Development of Latin America’s first dedicated 1,000 tonne per day high-efficiency solar glass plant and the commercialization of antimony-free solar glass designed for next-generation photovoltaic performance.
  • Energy Storage: Advancement of long-duration, silica-based thermal storage systems and related technologies to decarbonize industrial heat and unlock grid flexibility.
  • Energy Solutions: AI-enabled energy management, control systems, and turnkey electrification solutions that reduce costs and optimize renewable generation for commercial and industrial customers.

With disciplined execution, strategic partnerships, and an unwavering commitment to best-in-class ESG practices, Homerun is focused on converting milestones into markets-creating a scalable, vertically integrated platform for clean energy manufacturing in the Americas.

On behalf of the Board of Directors of Homerun Resources Inc.:

‘Brian Leeners’

Brian Leeners, CEO & Director
brianleeners@gmail.com / +1 604-862-4184 (WhatsApp)

Tyler Muir, Investor Relations
info@homerunresources.com / +1 306-690-8886 (WhatsApp)

FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE

The information contained herein contains ‘forward-looking statements’ within the meaning of applicable securities legislation. Forward-looking statements relate to information that is based on assumptions of management, forecasts of future results, and estimates of amounts not yet determinable. Any statements that express predictions, expectations, beliefs, plans, projections, objectives, assumptions or future events or performance are not statements of historical fact and may be ‘forward-looking statements’.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

This news release does not constitute an offer to sell or a solicitation of an offer to buy any securities in the United States. The securities have not been and will not be registered under the United States Securities Act of 1933, as amended (the ‘U.S. Securities Act’) or any state securities laws and may not be offered or sold within the United States or to U.S. Persons unless registered under the U.S. Securities Act and applicable state securities laws or an exemption from such registration is available.

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/275995

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(TheNewswire)

LiDAR, or Light Detection and Ranging, is a remote sensing technology that uses laser light to ‘see through’ vegetation and soil cover to measure distances, with 15-30 cm scale accuracy, to underlying rock surfaces.  In this way, it can map out features such as structures and lithological contacts that can be related to mineralization but may not be exposed at surface.  The survey also included colour aerial photography with 10-15 cm resolution that will assist in surface exploration and planning of infrastructure upgrades.

‘Although we have been able to follow and map out the Dos de Mayo vein system along strike for approximately 1,600 metres so far, our geologists are restricted by the amount of outcrop exposure ,’ stated Robert Archer, Pinnacle’s President & CEO.  ‘The LiDAR survey should allow us to ‘connect the dots’ along this structural trend and allow us to better define not only the main vein but parallel and splay veins nearby.  This knowledge, along with additional features such as flexures and fault offsets in the vein structures, will be crucial for interpreting the geological environment and planning the surface drill program.  In addition, LiDAR is known for its ability to detect subtle and sometimes buried features such as old mine workings, overgrown pits and trenches that could lead to the discovery of previously unknown mineralization.’

Qualified Person

Mr. Jorge Ortega, P. Geo, a Qualified Person as defined by National Instrument 43-101, and the author of the NI 43-101 Technical Report for the Potrero Project, has reviewed, verified and approved for disclosure the technical information contained in this news release.

About the Potrero Property

El Potrero is located in the prolific Sierra Madre Occidental of western Mexico and lies within 35 kilometres of four operating mines, including the 4,000 tonnes per day (tpd) Ciénega Mine (Fresnillo), the 1,000 tpd Tahuehueto Mine (Luca Mining) and the 250 tpd Topia Mine (Guanajuato Silver).

High-grade gold-silver mineralization occurs in a low sulphidation epithermal breccia vein system hosted within andesites of the Lower Volcanic Series and has three historic mines along a 500 metre strike length.  The property has been in private hands for almost 40 years and has never been systematically explored by modern methods, leaving significant exploration potential.

A previously operational 100 tpd plant on site can be refurbished / rebuilt and historic underground mine workings rehabilitated at relatively low cost in order to achieve near-term production once permits are in place. The property is road accessible with a power line within three kilometres.

Pinnacle will earn an initial 50% interest immediately upon commencing production.  The goal would then be to generate sufficient cash flow with which to further develop the project and increase the Company’s ownership to 100% subject to a 2% NSR.  If successful, this approach would be less dilutive for shareholders than relying on the equity markets to finance the growth of the Company.

About Pinnacle Silver and Gold Corp.

Pinnacle is focused on the development of precious metals projects in the Americas.  The high-grade Potrero gold-silver project in Mexico’s Sierra Madre Belt hosts an underexplored low-sulphidation epithermal vein system and provides the potential for near-term production . In the prolific Red Lake District of northwestern Ontario, the Company owns a 100% interest in the past-producing, high-grade Argosy Gold Mine and the adjacent North Birch Project with an eight-kilometre-long target horizon . With a seasoned, highly successful management team and quality projects, Pinnacle Silver and Gold is committed to building long -term , sustainable value for shareholders.

Signed: ‘Robert A. Archer’

President & CEO

For further information contact :

Email: info@pinnaclesilverandgold.com

Tel.:  +1 (877) 271-5886 ext. 110

Website: www.pinnaclesilverandgold.com

Neither the TSX Venture Exchange nor the Investment Industry Regulatory Organization of Canada accepts responsibility for the adequacy or accuracy of this release .

Copyright (c) 2025 TheNewswire – All rights reserved.

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Here’s a quick recap of the crypto landscape for Monday (November 24) as of 9:00 a.m. UTC.

Get the latest insights on Bitcoin, Ether and altcoins, along with a round-up of key cryptocurrency market news.

Bitcoin and Ether price update

Bitcoin (BTC) was priced at US$86,884.76, down by 1 percent over 24 hours. Its lowest price of the day was US$85,545.99, and its highest was US$87,995.12.

Bitcoin price performance, November 24, 2025.

Chart via TradingView

Ether (ETH) was at US$2,835.53, down 0.2 percent over 24 hours. Its lowest price on Monday was US$2,770.21 and its highest was US$2,881.29.

Altcoin price update

  • XRP (XRP) was priced at US$2.07, up by 1.2 percent over 24 hours. Its lowest price of the period was US$2.03 and its highest was US$2.10.
  • Solana (SOL) was trading at US$130.37, down by 0.7 percent over 24 hours. Its lowest price of the day was US$128.65 and its highest was US$133.96.

Today’s crypto news to know

Wall Street firms scale back MicroStrategy exposure

Fresh filings show major US asset managers cut their exposure to Strategy (NASDAQ:MSTR) (formerly MicroStrategy) through the third quarter, reducing positions by more than US$5 billion as the stock’s premium to its Bitcoin holdings continued to compress.

The company’s mNAV multiple has fallen close to parity as the market reassesses how much extra value investors are willing to assign to a Bitcoin-heavy corporate balance sheet. Pressure intensified after JPMorgan warned clients that MSCI is weighing whether companies with more than half of their assets in crypto should remain eligible for major equity indexes.

Index exclusion would not affect operations, Strategy chairman Michael Saylor said, but it has accelerated debate about the long-term viability of the digital-asset-treasury model.

Filings indicate that investment firms like BlackRock, Vanguard, and Capital International all pared their holdings, even as Bitcoin remained relatively stable earlier in the quarter.

Analysts say institutional investors could continue reducing exposure to corporate BTC proxies if volatility persists, as Bitcoin now faces one of its sharpest drawdowns since 2022.

JPMorgan hit by backlash After new debanking allegations

JPMorgan Chase & Co. (NYSE:JPM) is facing an uproar from Bitcoin advocates after Strike CEO Jack Mallers disclosed that the bank abruptly closed his personal accounts in September without explanation.

According to a report by the The Street, the news came just days after a JPMorgan research note highlighted MSCI’s proposal to exclude companies holding more than 50 percent. of their assets in crypto from its flagship indexes.

The move was widely interpreted as targeting Bitcoin-treasury firms such as Strategy. Crypto advocates quickly labeled the developments a revival of “Operation Chokepoint 2.0,” arguing that major banks and regulators are again restricting access to financial services for digital-asset firms and their executives.

The controversy has prompted calls across Bitcoin forums and social media for a coordinated boycott of JPMorgan, echoing earlier grievances about sudden account closures dating back to 2017.

Michael Burry debuts newsletter after Scion shutdown

Michael Burry, best known for his prescient bet against the US housing market in 2008, has launched a paid Substack newsletter soon after closing his hedge fund, Scion Asset Management.

In his introductory post, Burry emphasized that the move does not mark retirement but rather a shift toward writing without the regulatory constraints that accompany professional money management.

Priced at US$39 per month, the newsletter quickly drew more than 21,000 subscribers. Early essays revisit his trading history during the dot-com era and outline why he views today’s AI-driven boom as a supply-glutted bubble primed for correction.

With Scion now closed, Burry says the newsletter will become his primary outlet for analysis as he continues to track what he views as speculative excess building across technology markets.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

Securities Disclosure: I, Meagen Seatter, hold no direct investment interest in any company mentioned in this article.

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Locksley Resources Ltd. (ASX: LKY,OTC:LKYRF; OTCQX: LKYRF) announced the company has appointed Stacy Newstead to its advisory board as Strategic Advisor-Materials Strategy.

Ms. Newstead brings more than 20 years of experience across U.S. government, defense and industrial sectors. She currently serves as Materials Strategy and Risk Manager at Lockheed Martin, where she leads initiatives to secure domestic and allied sources of key materials vital to U.S. defense manufacturing and national security. Her work focuses on assessing and mitigating material pricing and geopolitical risk across supply chains that underpin critical technologies including munitions, batteries, and aerospace systems. Her prior roles include senior program leadership at Huntington Ingalls Industries and Textron Systems, as well as CEO of the U.S. subsidiary of Evolution Energy Minerals, where she led onshoring initiatives for graphite and advanced battery materials. More information can be found here:  https://cdn-api.markitdigital.com/apiman-gateway/ASX/asx-research/1.0/file/2924-03026929-6A1298599&v=undefined.

‘Stacy’s appointment strengthens Locksley’s ability to engage with U.S. partners and access federal programs supporting domestic critical mineral supply chains,’ said Kerrie Matthews, Locksley CEO. ‘Her deep understanding of defense material supply chains, coupled with her leadership at Lockheed Martin, brings exceptional strategic value to Locksley as we advance our mine-to-market development of American sourced antimony and rare earths.’

Matthews added that Newstead’s perspective on material security and risk is expected to help guide engagement with U.S. industry and government stakeholders as Locksley scales from pilot to commercial operations.

Locksley Resources (https://www.locksleyresources.com.au) is focused on critical minerals in the U.S. The company is actively advancing the Mojave Project in California, targeting rare earth elements (REEs) and antimony. Locksley is executing a mine-to-market strategy for antimony, aimed at reestablishing domestic supply chains for critical materials, underpinned by strategic downstream technology partnerships with leading U.S. research institutions and industry partners. This targeted approach, combined with resource development with innovative processing and separation technologies, positions Locksley to play a key role in advancing U.S. critical materials independence.

Contact: Beverly Jedynak, beverly.jedynak@viriathus.com, 312-943-1123; 773-350-5793 (cell)

View original content:https://www.prnewswire.com/news-releases/locksley-strengthens-us-defense-supply-chain-strategy-with-appointment-of-lockhead-martin-materials-leader-to-advisory-board-302624138.html

SOURCE Locksley Resources

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 FPX Nickel Corp. (TSXV: FPX) (OTCQB: FPOCF) (‘FPX’ or the ‘Company’) is pleased to announce that it has successfully obtained UL Solutions ECOLOGO® certification, a leading third-party verification program for sustainable practices in the mineral exploration sector.

‘Securing ECOLOGO® certification from UL Solutions is a significant achievement for FPX,’ said Martin Turenne, FPX’s President and CEO. ‘It demonstrates our team’s commitment to going beyond regulatory requirements and embedding sustainable practices into our work. Importantly, this certification underscores our respect for Indigenous rights and the communities where we operate, and reflects our belief that responsible exploration is the foundation of successful project development.’

The ECOLOGO® certification is administered by UL Solutions and is recognized across Canada as a rigorous standard for environmental, social, and governance (‘ESG‘) performance. Designed to promote responsible natural resource development, the ECOLOGO® program assesses exploration companies against criteria such as environmental protection, health and safety, respect for Indigenous rights, and community engagement.

‘Earning UL Solutions ECOLOGO® certification empowers mineral exploration companies to demonstrate independently verified leadership in environmental stewardship,’ said Ranee Valles, director and general manager of the Product Sustainability group at UL Solutions. ‘In an era where transparency drives investor confidence and regulatory compliance is non-negotiable, this certification not only differentiates certified companies in the marketplace but also fosters stronger trust with stakeholders and local communities.’

The certification process involved a comprehensive desktop audit of corporate policies and practices, as well as a field audit conducted during the 2025 Baptiste exploration program, to ensure alignment with leading ESG benchmarks. Significantly, FPX is the first company in Canada to achieve ECOLOGO® certification for a company with operations located outside of Quebec. FPX is also pleased to report that the certification process was completed from July to September 2025, reflecting strong corporate and field ESG policies and practices supporting an efficient and timely audit process.

For First Nations and local communities, ECOLOGO® certification provides assurance that FPX will continue to operate with transparency, accountability, and with a focus on minimizing environmental impacts. For investors, certification represents an additional layer of due diligence, strengthening the Company’s ESG profile and positioning it for success in an evolving investment landscape. FPX believes that responsible exploration is essential to building trusted relationships and to advancing projects that can deliver both economic and social value. The Company will continue to work closely with Indigenous rights holders, regulators, and local communities to ensure its activities align with the sustainability standards and best practices.

About the Baptiste Nickel Project

The Company’s Baptiste Nickel Project represents a large-scale greenfield discovery of nickel mineralization in the form of a sulphur-free, nickel-iron mineral called awaruite (Ni3Fe) hosted in an ultramafic/ophiolite complex.  The absence of sulphur and our ability to connect to the BC Hydro grid means that Baptiste has the potential to be one of the lowest carbon-intensive nickel producers in the world and will produce a very high-grade product that does not require any intermediate smelting or complex refining.  The Baptiste mineral claims cover an area of 453 km2 west of Middle River and north of Trembleur Lake, in central British Columbia.  In addition to the Baptiste Deposit itself, awaruite mineralization has been confirmed through drilling at several target areas within the same claims package, most notably at the Van Target which is located 6 km to the north of the Baptiste Deposit.  Since 2010, approximately US$55 million has been spent on the exploration and development of Baptiste.

FPX has conducted mineral exploration activities to date subject to the conditions of agreements with First Nations and keyoh holders. In 2024, the Province of British Columbia identified the Baptiste Nickel Project as the first project to be included in the Province’s new Critical Minerals Office (‘CMO’) concierge service initiative, a provincial strategy action to enable the prioritization of critical minerals projects in B.C. The CMO initiative is providing an excellent structure to proactively identify and address issues and opportunities ahead of the Project’s entry into the environmental assessment process.

About FPX Nickel Corp.

FPX Nickel Corp. is focused on the exploration and development of the Baptiste Nickel Project, located in central British Columbia, and other occurrences of the same unique style of naturally occurring nickel-iron alloy mineralization known as awaruite.  For more information, please view the Company’s website at https://fpxnickel.com/.

On behalf of FPX Nickel Corp.

‘Martin Turenne’
Martin Turenne, President, CEO and Director

Forward-Looking Statements

Certain of the statements made and information contained herein is considered ‘forward-looking information’ within the meaning of applicable Canadian securities laws. These statements address future events and conditions and so involve inherent risks and uncertainties, as disclosed in the Company’s periodic filings with Canadian securities regulators. Actual results could differ from those currently projected. The Company does not assume the obligation to update any forward-looking statement.

Neither the TSX Venture Exchange nor its Regulation Services Provider accepts responsibility for the adequacy or accuracy of this release.

SOURCE FPX Nickel Corp.

View original content to download multimedia: http://www.newswire.ca/en/releases/archive/November2025/24/c5350.html

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Harmony Gold Mining (NYSE:HMY,JSE:HAR) announced that it has approved development of its Eva Copper project in Queensland after completing an updated feasibility study, with an estimated capital of US$1.75 billion across a three-year window.

The South African miner said Monday (November24) that its board signed off on the Final Investment Decision for the Eva copper project, a 100-percent-owned project in northwest Queensland expected to deliver high margins and a long operating life.

Harmony plans to build a low strip-ratio open-pit mine capable of producing about 65,000 metric tons of copper concentrate annually during its first five years, with an average life-of-mine profile of roughly 60,000 metric tons of copper and 19,000 ounces of gold per year over an estimated 15-year span.

The mine will process about 18 million metric tons of ore per year and carry an all-in sustaining cost of approximately US$2.50 per pound.

CEO Beyers Nel said the feasibility results confirm the company’s shift toward a balanced gold-and-copper portfolio.

“The Eva Copper Feasibility Study delivers a strong, high-confidence outcome that positions Harmony for the next phase of growth as we continue building a high-quality, low-cost portfolio,” he said.

Nel also tied Eva Copper to Harmony’s expanding strategy, pointing to the company’s recently completed MAC Copper acquisition.

“Eva Copper, together with our recent MAC Copper acquisition, creates a compelling platform that brings together the enduring value of gold with the future-facing strength of copper, enhancing cash flow resilience across commodity cycles,” he said.

Last month, Harmony completed its US$1.01 billion acquisition of MAC Copper, giving the company full ownership of the high-grade CSA copper mine in New South Wales.

The company said the purchase builds on its strategic push to strengthen its copper position in Tier-1 jurisdictions. It also expects its two major Australian copper assets to deliver a combined 100,000 metric tons of copper annually once fully commissioned.

Meanwhile, the Eva Copper project was acquired by the company in October 2022 and has since completed 166,000 metres of drilling. The current two-million-metric-ton copper resource underpins the potential for future extensions to the mine’s life.

Harmony anticipates first production in the second half of 2028, a timeline it says aligns with a structural deficit in copper supply that could support stronger prices.

Board approval moves the project into the execution phase. Mobilization to site is expected in the third quarter of fiscal 2026, subject to amendments to the project’s Environmental Authority.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

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Glenstar Minerals Inc. (CSE: GSTR) (OTCQB: GSTRF) (FSE: VO20) (‘Glenstar’ or the ‘Company’) announces that it has granted a permit by the Bureau of Land Management (the ‘BLM’) to conduct the Phase 2 drill program at its Green Monster Project in southwestern Nevada.

The permit allows the Company to drill nine (9) holes over four (4) locations on the property and will be comprised of approximately 300 metres of strike length exploration. As currently planned, Glenstar will collar two (2) holes in the area of the primary drilling undertaken in the Phase 1 drill program; three (3) holes will focus on the area that is considered the ‘discovery’ zone 150 metres to the west of the primary Phase 1 drill site, and two (2) holes each at two (2) sites will be situated further west along what is believed to be the mineralized east-west trending belt.

The precise location of each drill hole is yet to be determined and will be decided upon review of the data gleaned from the previously announced Hybrid-Source Audio-Magnetotellurics Survey (the ‘HSAMT‘ or ‘Survey‘) that was conducted by Hasbrouck Geophysics, Inc. (‘Hasbrouck‘) of Prescott, Arizona and Advantage Geophysics, Inc. (‘Advantage‘) of Phoenix Arizona. This survey has now concluded and the results, along with the various data sets, will be contained in a final report that will be provided to the Company by Hasbrouck. This report is expected to be completed in early December and the results will be instrumental in determining the best, and most advantageous, location for each hole of the Phase 2 drill program.

The survey data was acquired at intervals of 50 metres along 13 lines and was conducted by a 3-person field team from Advantage, in conjunction with Hasbrouck. The data collected is currently being analysed and interpreted using sophisticated software that will convert it into two- and three-dimensional cross-sections in depth and/or elevation formats. The complete data set will be interpolated into a rectangular cube and horizonal depth slices, referenced to the surface. The final report will detail the methodology, data acquisition, processing, modeling, and interpretation of the data (see news release dated October 29, 2025) and will provide Glenstar’s geologic team with the information it needs to best determine the location of each drill hole in the Phase 2 program.

Glenstar CEO, Dave Ryan, stated, ‘The completion of the geophysical field work is an important milestone. Once we have the final report from Hasbrouck we will use this data to target sulfide facies mineralization in the area of the oxide mineralization that was intersected last summer.’

Project Background & Recent Exploration Work

The Green Monster Property is comprised of 35 federal lode claims covering ~700 acres located in Clark County, Nevada, on the west trending spur of the Spring Mountains and is approximately 40 miles southwest of Las Vegas. Until the recent drill program in May of 2025, no drilling was ever conducted on the property, but the Company’s previous identification of robust nickel-copper with anomalous cobalt from sampling work done in 2022 indicated that several targets were ideal for shallow RC drilling (see news releases dated May 28, 2025, and July 16, 2025).

Glenstar acquired the Green Monster Property and conducted initial groundwork in 2022 that included reconnaissance geologic mapping, surface rock sampling, soil sampling, and a drone magnetic survey. Channel sampling across the exposed back of a raise off the main shaft returned 1.18 meters of 3.77% Cu (Copper), 3.06% Ni (Nickel), 0.21% Co (Cobalt) and 6.83% Zn (Zinc). These values are well in excess of select dump samples from historical underground workings and represent in-place, vein style mineralization. Sampling of oxide and sulfide bearing boulders directly downhill of the patented workings has confirmed the presence of very high zinc (>10%) and silver (>200ppm), as well as copper, uranium, and lead. (Sampling results provided above were previously published in the Green Monster Project NI 43-101 Technical Report dated June 20, 2023, Section 7.5).

About Glenstar Minerals Inc.

Glenstar is a mineral exploration company with a focus on polymetallic minerals. These elements are classified as critical minerals and are essential in the manufacturing of sophisticated electronics and other vital energy technologies. The Company’s mission is to leverage its knowledge and connections to explore, acquire, and develop critical mineral and energy metal properties throughout the world.

Glenstar’s shares trade on the Canadian Securities Exchange (CSE) under the symbol ‘GSTR’, on the Frankfurt Stock Exchange under the symbol ‘VO20’, and on the Over-the-Counter market (OTCQB) in the United States under the symbol ‘GSTRF’.

Robert Marvin, P.Geo (ONT) is the qualified person as defined by National Instrument 43-101 and is the independent consulting geologist for Glenstar Minerals Inc., who has examined the Green Monster and Wildhorse properties on the ground numerous times since 2022 and 2024 respectively. All fieldwork relating to geologic observations and sampling as reported herein, has been directly overseen by Mr. Marvin who supervised the preparation of, and has reviewed and approved, the technical information in this release.

ON BEHALF OF THE BOARD,

‘David Ryan’
President & CEO

Further information regarding the Company can be found on SEDAR+ at www.sedarplus.ca, by visiting the Company’s website at www.glenstar.ca or by contacting the Company directly at 604-449-2810.

Neither Canadian Securities Exchange nor its Regulation Services Provider (as that term is defined in policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release.

Cautionary Statement Regarding Forward-Looking Information Certain information contained in this news release constitutes ‘forward-looking information’ or ‘forward-looking statements’ (collectively, ‘forward- looking information’). Without limiting the foregoing, such forward-looking information includes statements regarding the process and completion of any Offering, the use of proceeds of the Offering and any statements regarding the Company’s business plans, expectations and objectives. In this news release, words such as ‘may’, ‘would’, ‘could’, ‘will’, ‘likely’, ‘believe’, ‘expect’, anticipate’, ‘intend’, ‘plan’, ‘estimate’ and similar words and the negative form thereof are used to identify forward-looking information.

Forward-looking information should not be read as guarantees of future performance or results, and will not necessarily be accurate indications of whether, or the times at or by which, such future performance will be achieved. Mineral exploration is subject to risks and uncertainties and there is no assurance that any potential results or findings that may be suggested in this press release will ultimately happen. Forward-looking information is based on information available at the time and/or the Company management’s good faith belief with respect to future events and is subject to known or unknown risks, uncertainties, assumptions and other unpredictable factors, many of which are beyond the Company’s control. For additional information with respect to these and other factors and assumptions underlying the forward-looking information made in this news release, see the Company’s most recent Management’s Discussion and Analysis and financial statements and other documents filed by the Company with the Canadian securities commissions and the discussion of risk factors set out therein. Such documents are available at www.sedarplus.ca under the Company’s profile and on the Company’s website. The forward-looking information set forth herein reflects the Company’s expectations as at the date of this news release and is subject to change after such date.

This release may contain certain forward‐looking statements with respect to the financial condition, results of operations and business of the Company and certain of the plans and objectives of the Company with respect to the same. By their nature, forward‐looking statements involve risk and uncertainty because they relate to events and depend on circumstances that will occur in the future and there are many factors that could cause actual results and developments to differ materially from those expressed or implied by these forward‐looking statements.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy any securities, nor shall there be any sale of securities in any state in the United States in which such offer, solicitation or sale would be unlawful. The securities referred to herein have not been and will not be registered under the United States Securities Act of 1933, as amended, and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements. This release may contain statements within the meaning of safe harbour provisions as defined under securities laws and regulations. We seek safe harbour.

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/275670

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